MyBibliography
Google Scholar Citations

Selected Publications

Guo DF, Reho JJ, Morgan DA, Rahmouni K: Cardiovascular Regulation by the Neuronal BBSome. Hypertension 2020; in press

López M, Varela L, Vázquez MJ, Rodríguez-Cuenca S, González R, Velagapudi VR, Morgan DA, Schoenmakers E, Agassandian K, Lage R, Martínez de Morentin PB, Tovar S, Nogueiras R, CarlingD, Lelliott CJ, Gallego R, Orešič M, Chatterjee K, Saha AK, Rahmouni K, Diéguez C, Vidal-Puig A: Dysregulation of hypothalamic AMPK and fatty acid metabolism mediates hyperthyroidism-induced alterations in energy balance. Nature Medicine 2010; 16: 1001-8.

Harlan SM, Morgan DA, Agassandian K, Guo DF, Cassell MD, Sigmund CD, Mark AL, Rahmouni K: Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation. Circulation Research 2011; 108: 808-12.

Zhang Z, Liu X, Morgan DA, Kuburas A, Thedens DR, Russo AF, Rahmouni K: Neuronal receptor activity modifying protein-1 promotes energy expenditure in mice. Diabetes 2011; 60: 1063-71.

Whittle AJ, Carobbio S, Slawik M, Vázquez MJ, Morgan DA, Csikasz R, Virtue S, Dale M, Cannon B, Rahmouni K, López M, Vidal-Puig A: Bmp8b increases brown adipose tissue thermogenesis through both central and peripheral actions. Cell 2012, 149: 871-885.

Harlan SM, Guo DF, Morgan DA, Fernandes-Santos C, Rahmouni K: Hypothalamic mTORC1 signaling controls sympathetic nerve activity and arterial pressure and mediates leptin effects. Cell Metabolism 2013; 17:599-606.

Owen BM, Ding X, Morgan DA, Coate KC, Bookout AL, Rahmouni K, Kliewer SA, Mangelsdorf DJ: FGF21 Acts Centrally to Induce Sympathetic Nerve Activity, Energy Expenditure and Weight Loss. Cell Metabolism 2014, 20:670-7.

Tanida M, Yamamoto N, Morgan DA, Kurata Y, Shibamoto T, Rahmouni K: Leptin receptor signaling in the hypothalamus regulates hepatic autonomic nerve activity via PI3K and AMPK. Journal of Neuroscience 2015; 35:474–484.

Morgan DA, McDaniel L, Yin T, Khan M, Jiang J, Acevedo M, Walsh S, Ponto L, Norris A, Lutter M, Rahmouni K, Cui H: Regulation of Glucose Tolerance and Sympathetic Activity by MC4R Signaling in the Lateral Hypothalamus. Diabetes 2015; 64:1976-87.

Starks RD, Beyer AM, Guo DF, Boland L, Zhang Q, Sheffield VC, Rahmouni K: Regulation of Insulin Receptor Trafficking by Bardet Biedl Syndrome Proteins. PLOS Genetics 2015; 11(6):e1005311.

Von Holstein-Rathlou S, BonDurant L, Peltekian L, Naber MC,, Yin TC, Claflin KE, Urizar AI, Madsen AN, Ratner C, Holst B, Karstoft K, Vandenbeuch A, Anderson CB, Cassell MD, Thompson AP, Solomon TPJ, Rahmouni K, Kinnamon SC, Pieper AA, Gillum MP, Potthoff MJ: FGF21 Underlies the Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver. Cell Metabolism 2016; 23:335-343.

Guo DF, Cui H, Zhang Q, Morgan DA, Thedens DR, Nishimura D, Grobe JL, Sheffield VC, Rahmouni K: The BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane. PLOS Genetics 2016, 12: e1005890.

Steculorum SM, Ruud J , Karakasilioti I, Backes H, Ruud LE, Timper K, Hess M, Tsaousidiou E, Mauer J, Vogt MC, Paeger L, Bremser S, Klein AC, Morgan DA, Frommolt P, Brinkkötter PT, Benzing T, Rahmouni K, Wunderlich FT, Kloppenburg P, Brüning JC. AgRP-Neurons Control Systemic Insulin Sensitivity via Myostatin-Expression in BAT. Cell 2016; 165:125-38.

Flak JN, Arble D, Pan W, Patterson C, Lanigan T, Goforth PB, Sacksner J, Joosten M, Morgan DA, Allison MB, Hayes J, Feldman E, Seeley RJ, Olson DP, Rahmouni K, Myers Jr MG: A leptin-regulated circuit controls glucose mobilization during noxious stimuli. Journal of Clinical Investigation 2017; 127(8):3103-3113.

Lan T, Morgan DA, Rahmouni K, Sonoda J, Fu X, Burgess SC, Holland WL, Kliewer SA, Mangelsdorf DJ: FGF19, FGF21 and an FGFR1/β-Klotho-activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia. Cell Metabolism 2017; 26(5):709-718.e3.

Bell BB, Harlan SM, Morgan DA, Guo DF, Cui H, Rahmouni K: Differential Contribution of POMC and AgRP Neurons to the Regulation of Regional Autonomic Nerve Activity by Leptin. Molecular Metabolism 2018; 8:1-12.

Brandt C, Nolte H, Henschke S, Ruud LE, , Awazawa M, Morgan DA, Gabel P, Sprenger HG, Hess M, Günter S, Langer T, Rahmouni K, Krüger M, Brüning JC: Sensory Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of Liver mTOR Activation. Cell 2018; 175(5):1321-1335.

Nakagawa P, Nair AR, Agbor LN, Gomez J, Wu J, Zhang SY, Lu KT, Morgan DA, Rahmouni K, Grobe JL, Sigmund CD. Increased Susceptibility of Mice Lacking Renin-b to Angiotensin II-Induced Organ Damage. Hypertension. 2020 Aug;76(2):468-477.

Deng G, Morselli LL, Wagner VA, Balapattabi K, Sapouckey SA, Knudtson KL, Rahmouni K, Cui H, Sigmund CD, Kwitek AE, Grobe JL. Single-Nucleus RNA Sequencing of the Hypothalamic Arcuate Nucleus of C57BL/6J Mice After Prolonged Diet-Induced Obesity. Hypertension. 2020 Aug;76(2):589-597.

Jiang J, Morgan DA, Cui H, Rahmouni K.: Activation of hypothalamic AgRP and POMC neurons evokes disparate sympathetic and cardiovascular responses. Am J Physiol Heart Circ Physiol. 2020 Nov 1;319(5):H1069-H1077.

Wu J, Agbor LN, Fang S, Mukohda M, Nair AR, Nakagawa P, Sharma A, Morgan DA, Grobe JL, Rahmouni K, Weiss RM, McCormick JA, Sigmund CD. Failure to vasodilate in response to salt loading blunts renal blood flow and causes salt-sensitive hypertension. Cardiovasc Res. 2021 Jan 1;117(1):308-319.

Jing Wu and Larry N Agbor and Shi Fang and Masashi Mukohda and Anand R Nair and Pablo Nakagawa and Avika Sharma and Donald A Morgan and Justin L Grobe and Kamal Rahmouni and Robert M Weiss and James A McCormick and Curt D Sigmund.: Failure to vasodilate in response to salt loading blunts renal blood flow and causes salt-sensitive hypertension. Cardiovascular Research, Volume 117, Issue 1, 1/1/2021, Page(s) 308-319, DOI: 10.1093/cvr/cvaa147

John J. Reho and Deng-Fu Guo and Donald A. Morgan and Kamal Rahmouni.: mTORC1 (Mechanistic Target of Rapamycin Complex 1) Signaling in Endothelial and Smooth Muscle Cells Is Required for Vascular Function. Hypertension, Volume 77, Issue 2, 2/1/2021, Page(s) 594-604, DOI: 10.1161/HYPERTENSIONAHA.120.14708

Rouabhi M, Guo DF, Morgan DA, Zhu Z, López M, Zingman L, Grobe JL, Rahmouni K.: BBSome ablation in SF1 neurons causes obesity without comorbidities. Molecular Metabolism, Volume 48, Issue  , 6/1/2021, Page(s) 101211, DOI: 10.1016/j.molmet.2021.101211